Research Frontiers in Computational Biology

Explore cutting-edge studies, algorithms, and computational models transforming biological research

Research Articles

Decoding Viral Evolution: How AlphaFold2 Accelerates SARS-CoV-2 Spike Variant Analysis for Drug and Vaccine Development

This article explores the transformative application of DeepMind's AlphaFold2 in the study of SARS-CoV-2 spike protein variants.

Penelope Butler
Jan 09, 2026

Beyond Structure: How AlphaFold2 is Revolutionizing Protein Function Prediction for Drug Discovery

This article provides a comprehensive guide for researchers, scientists, and drug development professionals on leveraging AlphaFold2 for protein function prediction.

Emma Hayes
Jan 09, 2026

Beyond Structure: A Practical Guide to Predicting Catalytic and Binding Sites with AlphaFold2

This comprehensive guide explores how AlphaFold2, the revolutionary protein structure prediction tool, is being repurposed and adapted to predict catalytic and ligand-binding sites.

Genesis Rose
Jan 09, 2026

Deconstructing AlphaFold2: A Technical Deep Dive into the AI That Solved Protein Folding

This article provides a comprehensive technical analysis of DeepMind's AlphaFold2 deep learning architecture, tailored for researchers, scientists, and drug development professionals.

Christian Bailey
Jan 09, 2026

AlphaFold2 for Antibody Design: A Practical Guide to Accelerating Therapeutic Development

This article provides a comprehensive overview of AlphaFold2's revolutionary role in antibody structure prediction for therapeutic development.

Kennedy Cole
Jan 09, 2026

Decoding Protein Folding: A Deep Dive into AlphaFold2 and RoseTTAFold Training Data & AI Methodology

This article provides a comprehensive technical analysis for researchers and drug development professionals on the foundational data and advanced methodologies behind AlphaFold2 and RoseTTAFold.

Skylar Hayes
Jan 09, 2026

AlphaFold2 vs. Robetta vs. trRosetta: A Comprehensive Guide to Protein Structure Prediction and Validation with Molecular Dynamics

This guide provides researchers and drug development professionals with a practical framework for evaluating, utilizing, and validating protein structure predictions from leading AI tools AlphaFold2, Robetta, and trRosetta.

Jacob Howard
Jan 09, 2026

Unlocking Protein Folding: A Deep Dive into AlphaFold2's Evoformer Neural Network Architecture

This article provides a comprehensive analysis of the Evoformer, the core neural network engine within DeepMind's revolutionary AlphaFold2 system.

Brooklyn Rose
Jan 09, 2026

AlphaFold2 Evoformer Explained: Architecture, Mechanisms, and Applications in Protein Science

This article provides a comprehensive technical overview of the Evoformer module, the central engine of DeepMind's AlphaFold2.

Elizabeth Butler
Jan 09, 2026

AlphaFold-Multimer: A Comprehensive Guide to Predicting and Validating Protein Complex Structures for Drug Discovery

This article provides a complete resource for researchers, scientists, and drug development professionals on leveraging AlphaFold-Multimer for accurate protein complex prediction.

Nathan Hughes
Jan 09, 2026

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