Research Frontiers in Computational Biology

Explore cutting-edge studies, algorithms, and computational models transforming biological research

Research Articles

How Machine Learning is Revolutionizing Biomarker Discovery: From Multi-Omics Integration to Clinical Validation

This article provides a comprehensive overview of the transformative impact of machine learning (ML) and artificial intelligence (AI) on biomarker discovery for researchers, scientists, and drug development professionals.

Hudson Flores
Nov 26, 2025

AlphaFold2: Revolutionizing Protein Structure Prediction in Biomedical Research and Drug Discovery

This article provides a comprehensive overview of AlphaFold2 (AF2), the artificial intelligence system that has transformed computational biology by predicting protein structures from amino acid sequences with atomic-level accuracy.

Scarlett Patterson
Nov 26, 2025

A Comprehensive Guide to Molecular Dynamics Simulation: From Foundational Protocols to Advanced Applications in Drug Discovery

This article provides a comprehensive guide to molecular dynamics (MD) simulation protocols, tailored for researchers, scientists, and professionals in drug development.

James Parker
Nov 26, 2025

How to Start in Computational Genomics: A 2025 Roadmap for Researchers and Drug Developers

This guide provides a comprehensive roadmap for researchers, scientists, and drug development professionals to launch a successful career in computational genomics.

Emma Hayes
Nov 26, 2025

Molecular Dynamics Simulations: A Comprehensive Guide for Drug Discovery and Biomedical Research

This article provides a comprehensive overview of molecular dynamics (MD) simulations, a powerful computational tool that reveals atomic-level details of biomolecular processes critical for drug discovery.

Amelia Ward
Nov 26, 2025

AI in Biology: Revolutionizing Discovery from Proteins to Precision Medicine

Artificial intelligence is fundamentally restructuring research paradigms across the biological sciences, enabling a shift from experience-driven to data-algorithm symbiosis.

Brooklyn Rose
Nov 26, 2025

Systems Biology Modeling: A Comprehensive Guide from Foundations to Clinical Applications in Drug Development

This article provides researchers, scientists, and drug development professionals with a comprehensive introduction to systems biology modeling, covering foundational concepts, methodological approaches, troubleshooting strategies, and validation techniques.

Zoe Hayes
Nov 26, 2025

Computational Biology for Beginners: A Guide to Foundational Concepts, Methods, and Applications for Researchers

This article provides a comprehensive primer for researchers, scientists, and drug development professionals embarking on their journey in computational biology.

Leo Kelly
Nov 26, 2025

Computational Biology vs Bioinformatics: A 2025 Guide for Biomedical Researchers

This article provides a comprehensive guide for researchers and drug development professionals on the distinct yet complementary roles of computational biology and bioinformatics.

Owen Rogers
Nov 26, 2025

Foundation Models in Bioinformatics: A New Era of AI-Driven Biological Discovery

Foundation Models (FMs) are instigating a paradigm shift in bioinformatics, offering powerful solutions to long-standing challenges such as limited annotated data and high data noise.

Nathan Hughes
Nov 26, 2025

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